This methylation profile is already acquired at the MBL stage3 and remains fairly stable as time passes. Nonetheless, some CLL have intratumor variability in particular regions, which can change the expression of quite a few genes and aid tumor evolution.71 Of Take note, this variability is bigger in U-CLL than https://situs-judi-mbl7700098.thelateblog.com/33016153/about-link-alternatif-mbl77