There exists a release of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors during the dorsal horn to lessen afferent discomfort transmission and generate analgesia. Thus, drugs like clonidine that focus on alpha-two receptors can affect the transmission of discomfort. Jun ten, 2024 · If clonidine https://wilhelmi596duo1.wikiconversation.com/user