Calcium (Ca2+) dysregulation is a hallmark of heart failure and is characterized by impaired Ca2+ sequestration into the sarcoplasmic reticulum (SR) by the SR-Ca2+-ATPase (SERCA). We recently discovered a micropeptide named DWORF (DWarf Open Reading Frame) that enhances SERCA activity by displacing phospholamban (PLN). a potent SERCA inhibitor. Here we show that DWORF has a higher app... https://www.ealisboa.com/top-save-RE-DESIGNED-Strikketoy-oppbevaring-Prosjekt-27-Sort-100-Skinn-great-save/